MOR Ophthalmology Dept., MOR Institute, Bnei Brak, Israel
Purpose: To present Infra-Red Auto Fluorescence (IRAF) – which highlights unique findings in the early, unremarkable stages of Central Serous Chorioretinopathy (CSCR) – and to assess the possible contribution of Optical Coherent Topography Angiography (OCTA) in locating Choroidal Neo-Vascular membranes during the acute, often chronic, stages of the disease. Results were compared to findings from Fluorescein Angiography (FA), Indocyanine Green Angiography (ICGA), Fundus Autofluorescence (FAF), Infra Red Imaging (IR), MultiColor imaging (MC), Confocal Blue Reflectance (CBR) and spectral-domain OCT (SD-OCT).
Results: IRAF – which records light emanating from Melanin in the Retinal Pigment Epithelium (RPE)- presented notable changes in areas both highlighted by FA and ICGA, as well as in areas not assessed as affected by other imaging modalities. OCTA – which records blood-flow in distinct retinal and sub-retinal layers – presented the appearance of new vessels in select cases where irregular RPE was noted under areas elevated by sub-retinal fluid.
Conclusion: IRAF, which presents previously undocumented changes in the appearance of the retina in asymptomatic CSCR eyes, stands to add to our non-invasive Multi-Modal Imaging options.
OCTA, unique in its ability to non-invasively outline micro-vasculature changes under the RPE, offers the opportunity to assess the presence of CNV in eyes with CSCR.